Leila - Bioinformatics (Level 1) Pathway

Week 1

Technical Area: The basics of R programming

Tools: The resources linked below the module

Soft Skills: Time management, Virtual collaboration and teamwork

Three achievement highlights:

  • Journal club
  • Downloading R/R Studio
  • Managing time

Tasks completed:

  • Downloading R/R Studio. Had some problem finding version 4.0 using the link but just googled it and got it.
  • Journal club (giving a presentation on a figure)

Week 2

Technical Area:

  • More familiarity with creating R Shiny app.
  • Downloading database
  • Using pheatmap package

Tools:

  • R Studio
  • Google
  • The help given in R Studio

Soft Skills:

  • Time management
  • Research skills
  • Asking for help

Three achievement highlights:

  • Making R Shiny App
  • Downloading database
  • Managing time

Snapshot of RShiny app created:

Tasks completed:

  • Downloading database. Had some trouble loading it but looked at the guide posted on the Stemaway site and realized that I needed to unzip using some software.
  • Creating R Shiny App. Had some trouble understanding what to do but used the cheat sheet and googling.
  • Creating a heatmap. Didn’t know how to view the variables(raw/df) but got helped by Kelly Zhang. Also had trouble figuring out which were cancer and normal cells, but got it by going back to the site where I got the data.
  • Downloaded Git and created GitHub account.

Week 3

Technical Area: Using pheatmap package

Tools:

  • R Studio
  • Google
  • The help given in R Studio

Soft Skills:

  • Time management
  • Research skills
  • Asking for help

Three achievement highlights:

  • Creating the heatmap
  • Understanding more about R
  • Managing time

The heatmap created with Kelly:

and

Tasks completed:

  • Creating a heatmap.
  • Understanding the other parts of module 3

Week 4

Technical Area: Using various packages

Tools:

  • R Studio
  • Google
  • The help given in R Studio

Soft Skills:

  • Time management
  • Research skills
  • Asking for help

Three achievement highlights:

  • Creating the volcano map
  • Understanding more about R
  • Managing time

The volcano plot created with Ananya:

Tasks completed:

  • Creating a volcano plot.
  • Understanding the other parts of module 4

Week 5

Technical Area: Using various packages

Tools:

  • R Studio
  • Google
  • The help given in R Studio

Soft Skills:

  • Time management
  • Research skills
  • Asking for help

Three achievement highlights:

  • Creating the gene-concept network
  • Understanding more about R
  • Managing time

The gene ontology network created with Ivan:

Tasks completed:

  • Creating a gene-concept network.
  • Understanding the other parts of module 5

Week 6

Technical Area: Using various packages and web-based applications.

Tools:

  • R Studio
  • Google
  • The help given in R Studio

Soft Skills:

  • Time management
  • Research skills
  • Asking for help

Three achievement highlights:

  • Using the web based applications to obtain gene ontologies.
  • Understanding the gene ontologies.
  • Managing time

Gene ontologies (top parts) in order of BP, MF, CC from DAVID and Enrichr, created with Aditi:

From DAVID:

From Enrichr:

image

image

image

Tasks completed:

  • Obtaining gene ontologies.
  • Understanding the other parts of module 6

Week 7-8

Technical Area: Using all the packages used in previous modules to analyze GSE4107 for the capstone project.

Tools:

  • R Studio
  • Google
  • The help given in R Studio
  • Previous work from the modules

Soft Skills:

  • Time management (especially since this was a bigger project than the modules so we had to plan it out more carefully)
  • Research skills
  • Asking for help
  • Virtual collaboration and teamwork

Three achievement highlights:

  • Finishing and presenting the capstone project along with group members(Ivan, Arian, Kelly, Ananya, Roman)
  • Understanding more about R and how all the modules come together
  • Finding literature about CCN1/Cyr61

Tasks completed:

  • Creating and presenting capstone project
  • Finishing up Stemaway